Neuronal density in the human retinal ganglion cell layer from 16-77 years
نویسندگان
چکیده
منابع مشابه
Cell generation, death, and retinal growth in the development of the hamster retinal ganglion cell layer.
During the early postnatal period in the hamster, the retinal ganglion cell layer grows, establishes its central connections, and undergoes substantial cell loss. In this study, we describe the development of the retinal ganglion cell layer with particular attention to the creation of local specializations in cell density. Changes in the number and spatial distribution of cells identified by a ...
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AIM To determine if retinal ganglion cell (RGC) loss influences the loss of surrounding RGCs to generate clustered patterns of cell death in human glaucoma. It is hypothesised that retinal ganglion cell loss accelerates the loss of surrounding cells to generate, at a local, cellular scale, clustered patterns of retinal of RGC death. The absence of these interactions would result in a diffuse pa...
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PURPOSE Pathophysiological events in the retinal ganglion cell layer (GCL) are a prominent feature of several optic neuropathies including glaucoma. The purpose of this study was to identify and catalog genes whose expression in the human retina is restricted to the GCL. METHODS Laser capture microdissection (LCM) technology was used to isolate tissue from the perimacular retina of three huma...
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Introduction: Alzheimer disease (AD) is the most common form of dementia worldwide. The modalities to diagnose AD are generally expensive and limited. Both the central nervous system (CNS) and the retina are derived from the cranial neural crest; therefore, changes in retinal layers may reflect changes in the CNS tissue. Optical coherence tomography (OCT) machine can show delicate retinal layer...
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Here we describe quantitatively the birth and death of the two separate populations of neurons, ganglion cells and displaced amacrine cells, in the mouse retinal ganglion cell layer (GCL). The two cell types, which are roughly equally numerous, were distinguished pre- and postnatally by labeling the ganglion cells retrogradely with fluorescent dye. Embryos were labeled cumulatively with bromode...
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ژورنال
عنوان ژورنال: The Anatomical Record
سال: 2000
ISSN: 0003-276X,1097-0185
DOI: 10.1002/1097-0185(20001001)260:2<124::aid-ar20>3.0.co;2-d